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U11 spliceosomal RNA : ウィキペディア英語版 | U11 spliceosomal RNA
The U11 snRNA (small nuclear ribonucleic acid) is an important non-coding RNA in the minor spliceosome protein complex, which activates the alternative splicing mechanism. The minor spliceosome is associated with similar protein components as the major spliceosome. It uses U11 snRNA to recognize the 5' splice site (functionally equivalent to U1 snRNA) while U12 snRNA binds to the branchpoint to recognize the 3' splice site (functionally equivalent to U2 snRNA). == Secondary structure of U11 snRNA == U11 snRNA has a stem-loop structure with a 5' end as splice site sequence (5' ss) and contains four stem loops structures (I-IV). A structural comparison of U11 snRNA between plants, vertebrates and insects shows that it is folded into a structure with a four-way junction at the 5’ site and in a stem loop structure at the 3’ site.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「U11 spliceosomal RNA」の詳細全文を読む
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